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Bergqvist C, Ezzedine K

PR3, as well as NE and MPO, were found to be elevated and catalytically active in the urine of patients with bladder cancer, but they were not detected in the urine of healthy controls (177, 178)

However, high doses of vitamin B12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Its important to note that these side effects are generally mild and temporary